Everything the Spanish National Activity Registry publishes about H. U. Reina Sofia between 2009 and 2023: 15 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.
Volume first
Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.
Transfers recorded per year — IVF/ICSI with own oocytesSee this chart’s data
Transfers recorded per year — IVF/ICSI with own oocytes
Year
Value
2009
271
2010
291
2011
281
2012
298
2013
279
2014
317
2015
269
2016
341
2017
321
2018
321
2019
313
2020
179
2021
301
2022
297
2023
377
Transfers recorded per year — Egg donationSee this chart’s data
Transfers recorded per year — Egg donation
Year
Value
2014
3
Results, year by year
Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.
IVF/ICSI with own oocytes · Under 35
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Under 35
Year
Fresh embryos
Frozen embryos
2009
35.4 – 49.3%
35.4 – 49.3%
2010
27 – 39.3%
27 – 39.3%
2011
28.6 – 42.4%
28.6 – 42.4%
2012
35.5 – 52.1%
34.9 – 50%
2013
33.8 – 52.4%
25 – 40.3%
2014
33.9 – 50.6%
16.4 – 61.4%
2015
24.6 – 42.1%
12.4 – 51.3%
2016
36.7 – 55.7%
19.2 – 51.4%
2017
32.6 – 51.7%
17.6 – 44.6%
2018
41.3 – 62.1%
16.7 – 40.4%
2019
27.7 – 48.9%
29.9 – 53%
2020
16.8 – 46.4%
18.6 – 50%
2021
16.3 – 38.5%
21.7 – 47.5%
2022
17.3 – 40.4%
10.3 – 28.6%
2023
12.5 – 30.6%
16.8 – 33.2%
IVF/ICSI with own oocytes · Between 35 and 39
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Between 35 and 39
Year
Fresh embryos
Frozen embryos
2009
11 – 23.2%
11 – 23.2%
2010
15.4 – 29.9%
15.4 – 29.9%
2011
25.7 – 41.5%
26.8 – 42.8%
2012
26.3 – 45%
22.8 – 38.8%
2013
21.4 – 38.2%
16.4 – 30.1%
2014
22.3 – 37.9%
3 – 41.4%
2015
20.8 – 37.9%
8.1 – 44%
2016
27.5 – 42.7%
10.8 – 42.5%
2017
28.3 – 45.3%
4.3 – 35.7%
2018
23.6 – 40.7%
12.1 – 42.5%
2019
29.8 – 49.4%
6.5 – 37.9%
2020
24.3 – 49.4%
0 – 28%
2021
20.8 – 39.9%
11.9 – 33.7%
2022
17.7 – 37.3%
11.4 – 33.9%
2023
15.6 – 33.3%
7.4 – 26.5%
IVF/ICSI with own oocytes · Over 40
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Over 40
Year
Fresh embryos
Frozen embryos
2009
0 – 0%
0 – 0%
2010
0 – 44.8%
0 – 44.8%
2011
0 – 67.4%
0 – 67.4%
2012
1.8 – 31.6%
1.4 – 28.2%
2013
0 – 30.5%
0 – 27.1%
2014
—
0 – 67.4%
2015
13.3 – 100%
—
2016
3 – 41.4%
0 – 100%
2017
0 – 30.6%
32.6 – 100%
2018
0 – 12.7%
0 – 55.1%
2019
23.5 – 59.3%
1.6 – 58.4%
2020
0 – 21.1%
—
2021
3.9 – 33.2%
0 – 42.9%
2022
0 – 26.8%
0 – 28.6%
2023
10.4 – 45.6%
—
Egg donation · Under 35
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Under 35
Year
Fresh embryos
Frozen embryos
2009
0 – 0%
0 – 0%
2010
0 – 0%
0 – 0%
2011
0 – 0%
0 – 0%
2012
0 – 0%
0 – 0%
2013
0 – 0%
0 – 0%
Egg donation · Between 35 and 39
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Between 35 and 39
Year
Fresh embryos
Frozen embryos
2009
0 – 0%
0 – 0%
2010
0 – 0%
0 – 0%
2011
0 – 0%
0 – 0%
2012
0 – 0%
0 – 0%
2013
0 – 0%
0 – 0%
Egg donation · Over 40
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Over 40
Year
Fresh embryos
Frozen embryos
2009
0 – 0%
0 – 0%
2010
0 – 0%
0 – 0%
2011
0 – 0%
0 – 0%
2012
0 – 0%
0 – 0%
2013
0 – 0%
0 – 0%
AIH — artificial insemination (partner’s sperm) · Under 40See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 40
Year
Under 40
2009
3.9 – 8.8%
2010
7.2 – 13.1%
2011
4.1 – 9%
2012
5.2 – 10.2%
2013
8.7 – 15.9%
2014
8.3 – 15.2%
AIH — artificial insemination (partner’s sperm) · Under 35See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 35
Year
Under 35
2015
9.5 – 18.8%
2016
7.6 – 17.1%
2017
4.9 – 14.6%
2018
6.5 – 19%
2019
12.2 – 24.4%
2020
3.1 – 15.1%
2021
8.9 – 22.6%
2022
6.6 – 16.2%
2023
4.7 – 13.5%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39See this chart’s data
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
Year
Between 35 and 39
2015
7.6 – 19.6%
2016
5.8 – 17.9%
2017
2.5 – 14.4%
2018
5.1 – 23.5%
2019
7.4 – 31.6%
2020
6.1 – 30.7%
2021
0 – 11.3%
2022
5.1 – 21%
2023
2.6 – 18.5%
AID — artificial insemination (donor sperm) · Under 40See this chart’s data
AID — artificial insemination (donor sperm) · Under 40
Year
Under 40
2009
6.6 – 20.2%
2010
16.3 – 33.2%
2011
12.7 – 28.4%
2012
10.1 – 21.7%
2013
17.7 – 34.7%
2014
19.4 – 39.6%
AID — artificial insemination (donor sperm) · Under 35See this chart’s data
AID — artificial insemination (donor sperm) · Under 35
Year
Under 35
2015
11.7 – 33.1%
2016
6.4 – 28.3%
2017
7.9 – 24.9%
2018
3.5 – 19.5%
2019
9.6 – 26.8%
2020
5.8 – 21.6%
2021
4.7 – 19.6%
2022
13.7 – 34.1%
2023
3.9 – 26.1%
AID — artificial insemination (donor sperm) · Between 35 and 39See this chart’s data
AID — artificial insemination (donor sperm) · Between 35 and 39
Year
Between 35 and 39
2015
4.8 – 19.9%
2016
4.2 – 16.2%
2017
4.5 – 18.9%
2018
11.6 – 36.2%
2019
4.8 – 25.6%
2020
5.4 – 27.9%
2021
12.9 – 29.3%
2022
1.8 – 14%
2023
8.2 – 25.6%
Year-by-year table
The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.
Year
Name in the registry
Cycles started
Transfers
Pregnancy per transfer (under 35)
Pregnancy per cycle (insemination)
Attribution
2009
H. U. Reina Sofia
100-500
271
35.4 – 49.3%
3.9 – 8.8%
Registro Nacional de Actividad 2009-Registro SEF
2010
H. U. Reina Sofia
100-500
291
27 – 39.3%
7.2 – 13.1%
Registro Nacional de Actividad 2010-Registro SEF
2011
H. U. Reina Sofia
100-500
281
28.6 – 42.4%
4.1 – 9%
Registro Nacional de Actividad 2011-Registro SEF
2012
H. U. Reina Sofia
100-500
298
35.5 – 52.1%
5.2 – 10.2%
Registro Nacional de Actividad 2012-Registro SEF
2013
H. U. Reina Sofia
100-500
279
33.8 – 52.4%
8.7 – 15.9%
Registro Nacional de Actividad 2013-Registro SEF
2014
H. U. Reina Sofia
100-500
320
33.9 – 50.6%
8.3 – 15.2%
Registro Nacional de Actividad 2014-Registro SEF
2015
H. U. Reina Sofia
100-500
269
24.6 – 42.1%
9.5 – 18.8%
Registro Nacional de Actividad 2015-Registro SEF
2016
H. U. Reina Sofia
100-500
341
36.7 – 55.7%
7.6 – 17.1%
Registro Nacional de Actividad 2016-Registro SEF
2017
H. U. Reina Sofia
100-500
321
32.6 – 51.7%
4.9 – 14.6%
Registro Nacional de Actividad 2017-Registro SEF
2018
H. U. Reina Sofia
100-500
321
41.3 – 62.1%
6.5 – 19%
Registro Nacional de Actividad 2018-Registro SEF
2019
H. U. Reina Sofia
100-500
313
27.7 – 48.9%
12.2 – 24.4%
Registro Nacional de Actividad 2019-Registro SEF
2020
H. U. Reina Sofia
100-500
179
16.8 – 46.4%
3.1 – 15.1%
Registro Nacional de Actividad 2020-Registro SEF
2021
H. U. Reina Sofia
100-500
301
16.3 – 38.5%
8.9 – 22.6%
Registro Nacional de Actividad 2021-Registro SEF
2022
H. U. Reina Sofia
100-500
297
17.3 – 40.4%
6.6 – 16.2%
Registro Nacional de Actividad 2022-Registro SEF
2023
H. U. Reina Sofia
100-500
377
12.5 – 30.6%
4.7 – 13.5%
Registro Nacional de Actividad 2023-Registro SEF
Gaps in the series, and how to read them
The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.
The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.
And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.
