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Amnios In Vitro Project, year by year

Everything the Spanish National Activity Registry publishes about Amnios In Vitro Project between 2014 and 2023: 10 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.

Volume first

Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.

Transfers recorded per year — IVF/ICSI with own oocytes
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Transfers recorded per year — IVF/ICSI with own oocytes
YearValue
201433
201542
201656
201742
201847
201925
202026
202121
202229
202314
Transfers recorded per year — Egg donation
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Transfers recorded per year — Egg donation
YearValue
201470
201579
201684
201786
201849
201926
202017
202110
202215
202312

Results, year by year

Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.

IVF/ICSI with own oocytes · Under 35
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Under 35
YearFresh embryosFrozen embryos
201426.7 – 80.9%0 – 86.7%
20150.2 – 46%0 – 55.1%
201610 – 90%0 – 67.4%
2017—7.9 – 64.8%
201832.6 – 100%0 – 100%
2019—0 – 86.7%
2020—15.4 – 84.6%
2021—1 – 99%
2022—0 – 67.4%
2023—4 – 71%
IVF/ICSI with own oocytes · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Between 35 and 39
YearFresh embryosFrozen embryos
20140 – 46.5%—
20150 – 62%0 – 55.1%
20164.3 – 49%23.1 – 88%
20172.5 – 64.1%0 – 82.9%
201812 – 76.9%—
201910 – 90%10 – 90%
20200 – 86.7%2.5 – 64.1%
20210 – 67.4%100 – 100%
20220 – 67.4%46.4 – 99%
2023—1 – 99%
IVF/ICSI with own oocytes · Over 40
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Over 40
YearFresh embryosFrozen embryos
20140 – 46.5%—
20150 – 62%—
20160 – 28.7%—
201715.4 – 84.6%10 – 90%
20180 – 30.5%0 – 26.1%
20190 – 67.4%0 – 55.1%
2020—0 – 67.4%
2022100 – 100%0 – 55%
Egg donation · Under 35
  • Fresh embryos
  • Frozen embryos
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Egg donation · Under 35
YearFresh embryosFrozen embryos
201432.6 – 100%—
2015100 – 100%0 – 67.4%
2016—0 – 100%
2017100 – 100%—
2019—100 – 100%
Egg donation · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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Egg donation · Between 35 and 39
YearFresh embryosFrozen embryos
201419.4 – 68.1%—
201521.5 – 67.4%1 – 99%
201615.4 – 84.6%0 – 55.1%
201719 – 81%0 – 40.2%
201820.5 – 93.8%0 – 86.7%
20190 – 100%0 – 100%
2020100 – 100%0 – 100%
2023—0 – 86.7%
Egg donation · Over 40
  • Fresh embryos
  • Frozen embryos
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Egg donation · Over 40
YearFresh embryosFrozen embryos
201428.5 – 62.4%19.4 – 68.1%
201527.2 – 57.8%—
201641.2 – 69%2.7 – 39.4%
201742.2 – 73.6%8.6 – 39.7%
201829.2 – 76.7%5.2 – 40.2%
201923.1 – 88%13.8 – 69.6%
20200 – 86.7%7.9 – 64.8%
2021100 – 100%29 – 96%
2022100 – 100%13.8 – 69.6%
2023—23.1 – 88%
AIH — artificial insemination (partner’s sperm) · Under 40
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AIH — artificial insemination (partner’s sperm) · Under 40
YearUnder 40
20140 – 37.8%
AIH — artificial insemination (partner’s sperm) · Under 35
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AIH — artificial insemination (partner’s sperm) · Under 35
YearUnder 35
20150 – 40.2%
20210 – 67.4%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
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AIH — artificial insemination (partner’s sperm) · Between 35 and 39
YearBetween 35 and 39
2023100 – 100%
AID — artificial insemination (donor sperm) · Under 40
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AID — artificial insemination (donor sperm) · Under 40
YearUnder 40
20140 – 71.1%
AID — artificial insemination (donor sperm) · Under 35
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AID — artificial insemination (donor sperm) · Under 35
YearUnder 35
20150 – 40.2%
20166.7 – 60%
20172.5 – 64.1%
2018100 – 100%
20196.2 – 79.5%
202013.3 – 100%
AID — artificial insemination (donor sperm) · Between 35 and 39
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AID — artificial insemination (donor sperm) · Between 35 and 39
YearBetween 35 and 39
20150 – 46.5%
20170.5 – 49.5%
20210 – 55.1%
20220 – 67.4%

Year-by-year table

The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.

YearName in the registryCycles startedTransfersPregnancy per transfer (under 35)Pregnancy per cycle (insemination)Attribution
2014Amnios In Vitro ProjectNo data10326.7 – 80.9%0 – 37.8%Registro Nacional de Actividad 2014-Registro SEF
2015Amnios In Vitro ProjectNo data1210.2 – 46%0 – 40.2%Registro Nacional de Actividad 2015-Registro SEF
2016Amnios In Vitro ProjectNo data14010 – 90%6.7 – 60%Registro Nacional de Actividad 2016-Registro SEF
2017Amnios In Vitro ProjectNo data128No data2.5 – 64.1%Registro Nacional de Actividad 2017-Registro SEF
2018Amnios In Vitro ProjectNo data9632.6 – 100%100 – 100%Registro Nacional de Actividad 2018-Registro SEF
2019Amnios In Vitro ProjectNo data51No data6.2 – 79.5%Registro Nacional de Actividad 2019-Registro SEF
2020Amnios In Vitro ProjectNo data43No data13.3 – 100%Registro Nacional de Actividad 2020-Registro SEF
2021Amnios In Vitro ProjectNo data31No data0 – 67.4%Registro Nacional de Actividad 2021-Registro SEF
2022Amnios In Vitro Project100-50044No data0 – 67.4%Registro Nacional de Actividad 2022-Registro SEF
2023Amnios In Vitro ProjectNo data26No data100 – 100%Registro Nacional de Actividad 2023-Registro SEF

Gaps in the series, and how to read them

The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.

The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.

And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.

Official guide: how to interpret a centre’s data (PDF, in Spanish)

← Back to the Amnios In Vitro Project profile

Source: “Registro Nacional de Actividad 2023-Registro SEF” (Spanish National ART Activity Registry) — registrosef.com, retrieved 31 July 2026.