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Instituto Europeo de Fertilidad, year by year

Everything the Spanish National Activity Registry publishes about Instituto Europeo de Fertilidad between 2009 and 2023: 15 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.

Volume first

Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.

Transfers recorded per year — IVF/ICSI with own oocytes
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Transfers recorded per year — IVF/ICSI with own oocytes
YearValue
200998
2010119
2011112
2012203
2013240
2014248
2015193
2016220
2017183
2018171
2019182
2020156
2021160
2022148
2023123
Transfers recorded per year — Egg donation
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Transfers recorded per year — Egg donation
YearValue
200928
201039
201139
201282
201380
201489
2015112
201679
201768
201859
201969
202039
202147
202212
20236

Results, year by year

Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.

IVF/ICSI with own oocytes · Under 35
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Under 35
YearFresh embryosFrozen embryos
200925.6 – 57.8%78.3 – 99%
201029.2 – 62.2%63 – 90.9%
201116.8 – 46.4%28.9 – 60.5%
201227.8 – 56.7%32.4 – 59%
201331.3 – 60%36.6 – 62.6%
201420 – 46.7%17.9 – 50.8%
201530.9 – 63.5%19.1 – 73.3%
201640.9 – 80.8%25.9 – 65.8%
20173.8 – 46.2%23.8 – 76.2%
201831.9 – 80.6%35.4 – 82.2%
20190 – 49.4%26.9 – 73.1%
202058.6 – 97%57.1 – 100%
20210 – 42.9%25.7 – 63.2%
202239.2 – 89.4%21.5 – 67.4%
202312 – 76.9%31 – 73.7%
IVF/ICSI with own oocytes · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Between 35 and 39
YearFresh embryosFrozen embryos
200918.5 – 48.1%29.8 – 61%
201024 – 48.1%39.5 – 64.5%
201116.7 – 40.4%23.3 – 48.5%
201234.9 – 59%45.3 – 67.7%
201327.3 – 48.3%35.7 – 55.5%
201434 – 57.4%23.3 – 61.3%
201516.6 – 39.1%25.9 – 65.8%
201639.5 – 63.6%5.2 – 40.2%
201733.7 – 58.3%23.3 – 70.8%
201823.9 – 55%31.5 – 68.5%
201934.1 – 65.9%32 – 57.6%
202028.9 – 60.5%19.8 – 50.5%
202137.6 – 71.5%28.4 – 56.7%
202211 – 47.4%26 – 51.2%
20237.8 – 51.1%24.9 – 54.1%
IVF/ICSI with own oocytes · Over 40
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Over 40
YearFresh embryosFrozen embryos
20096.7 – 33.3%9.5 – 37.6%
20109.3 – 37.8%23.9 – 56.9%
201113.4 – 38.8%18.3 – 45.2%
20127 – 34.2%7.1 – 29.2%
201316 – 46.8%14.3 – 40.3%
201418.6 – 44.1%9.2 – 47.9%
201516.1 – 43%0 – 40.2%
201617.7 – 40.3%19.2 – 59.1%
201720.5 – 47.6%1.5 – 29.3%
201810.9 – 39.1%17.9 – 48.7%
20197.3 – 35.2%9.9 – 44%
20200 – 23.8%19.2 – 59.1%
202121.7 – 78.3%22.2 – 59.3%
2022—14.5 – 52.2%
20230 – 82.9%1.6 – 30.4%
Egg donation · Under 35
  • Fresh embryos
  • Frozen embryos
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Egg donation · Under 35
YearFresh embryosFrozen embryos
20090 – 100%100 – 100%
20100 – 71.1%0 – 71.1%
20111 – 99%32.6 – 100%
20126.2 – 79.5%20.5 – 93.8%
201344.9 – 100%100 – 100%
20140 – 46.5%13.3 – 100%
201516 – 74.9%—
2016100 – 100%—
2017—13.3 – 100%
2018—100 – 100%
2022—100 – 100%
Egg donation · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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Egg donation · Between 35 and 39
YearFresh embryosFrozen embryos
20096.2 – 79.5%100 – 100%
201016 – 74.9%16 – 74.9%
201164.6 – 100%100 – 100%
201231.2 – 83.1%78.1 – 100%
201353.9 – 93.5%65.8 – 99.2%
201440 – 93.3%—
201538.7 – 76.7%12 – 76.9%
201629.2 – 76.7%1 – 99%
201729 – 96%0.5 – 49.5%
201829 – 96%17.1 – 100%
201955.2 – 100%0 – 62%
2020100 – 100%20.5 – 93.8%
2021100 – 100%32.6 – 100%
2022100 – 100%—
2023—100 – 100%
Egg donation · Over 40
  • Fresh embryos
  • Frozen embryos
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Egg donation · Over 40
YearFresh embryosFrozen embryos
200917.3 – 58.9%17.3 – 58.9%
201013.7 – 50.3%70.7 – 98.9%
201139.1 – 73.4%63.6 – 92.3%
201217.2 – 51.8%16.3 – 46.6%
201322.7 – 56.1%36.3 – 69.9%
201427.3 – 59.2%13.7 – 50.3%
201545 – 76.1%17.2 – 54.8%
201626.6 – 60.9%8.7 – 45.9%
201713.2 – 53.5%4.9 – 38.6%
201831.9 – 80.6%26.7 – 62.9%
201961.4 – 95.1%40.7 – 76.5%
202042.8 – 90.5%47.8 – 95.1%
202135.2 – 84.8%20.4 – 61.5%
2022100 – 100%0 – 55%
2023—17.1 – 100%
AIH — artificial insemination (partner’s sperm) · Under 40
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AIH — artificial insemination (partner’s sperm) · Under 40
YearUnder 40
20093.2 – 29.1%
20100.8 – 20.3%
20114.1 – 34.4%
20120 – 35.8%
20139.2 – 30%
20141.7 – 18.7%
AIH — artificial insemination (partner’s sperm) · Under 35
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AIH — artificial insemination (partner’s sperm) · Under 35
YearUnder 35
20156 – 44%
20166.7 – 60%
20171 – 53.6%
20180 – 26.1%
20220 – 55.1%
20230 – 62%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
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AIH — artificial insemination (partner’s sperm) · Between 35 and 39
YearBetween 35 and 39
201516 – 74.9%
20170 – 40.2%
20180 – 71.1%
20220 – 46.5%
AID — artificial insemination (donor sperm) · Under 40
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AID — artificial insemination (donor sperm) · Under 40
YearUnder 40
20090 – 67.4%
20100 – 44.8%
20110 – 82.9%
20129.6 – 70.4%
20130.2 – 46%
20141.6 – 58.4%
AID — artificial insemination (donor sperm) · Under 35
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AID — artificial insemination (donor sperm) · Under 35
YearUnder 35
20160 – 55.1%
20180 – 67.4%
201913.3 – 100%
20210 – 71.1%
20220 – 100%
20230 – 37.8%
AID — artificial insemination (donor sperm) · Between 35 and 39
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AID — artificial insemination (donor sperm) · Between 35 and 39
YearBetween 35 and 39
20150 – 31.6%
20163.4 – 43.7%
20177.1 – 48.5%
20201.6 – 58.4%
20210 – 49.4%
20220 – 67.4%

Year-by-year table

The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.

YearName in the registryCycles startedTransfersPregnancy per transfer (under 35)Pregnancy per cycle (insemination)Attribution
2009Instituto Europeo de Fertilidad100-50012625.6 – 57.8%3.2 – 29.1%Registro Nacional de Actividad 2009-Registro SEF
2010Instituto Europeo de Fertilidad100-50015829.2 – 62.2%0.8 – 20.3%Registro Nacional de Actividad 2010-Registro SEF
2011Instituto Europeo de Fertilidad100-50015116.8 – 46.4%4.1 – 34.4%Registro Nacional de Actividad 2011-Registro SEF
2012Instituto Europeo de Fertilidad100-50028527.8 – 56.7%0 – 35.8%Registro Nacional de Actividad 2012-Registro SEF
2013Instituto Europeo de Fertilidad100-50032031.3 – 60%9.2 – 30%Registro Nacional de Actividad 2013-Registro SEF
2014Instituto Europeo de Fertilidad100-50033720 – 46.7%1.7 – 18.7%Registro Nacional de Actividad 2014-Registro SEF
2015Instituto Europeo de Fertilidad100-50030530.9 – 63.5%6 – 44%Registro Nacional de Actividad 2015-Registro SEF
2016Instituto Europeo de Fertilidad100-50029940.9 – 80.8%6.7 – 60%Registro Nacional de Actividad 2016-Registro SEF
2017Instituto Europeo de Fertilidad100-5002513.8 – 46.2%1 – 53.6%Registro Nacional de Actividad 2017-Registro SEF
2018Instituto Europeo de Fertilidad100-50023031.9 – 80.6%0 – 26.1%Registro Nacional de Actividad 2018-Registro SEF
2019Instituto Europeo de Fertilidad100-5002510 – 49.4%13.3 – 100%Registro Nacional de Actividad 2019-Registro SEF
2020Instituto Europeo de Fertilidad100-50019558.6 – 97%1.6 – 58.4%Registro Nacional de Actividad 2020-Registro SEF
2021Instituto Europeo de Fertilidad100-5002070 – 42.9%0 – 71.1%Registro Nacional de Actividad 2021-Registro SEF
2022Instituto Europeo de Fertilidad100-50016039.2 – 89.4%0 – 55.1%Registro Nacional de Actividad 2022-Registro SEF
2023Instituto Europeo de FertilidadNo data12912 – 76.9%0 – 62%Registro Nacional de Actividad 2023-Registro SEF

Gaps in the series, and how to read them

The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.

The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.

And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.

Official guide: how to interpret a centre’s data (PDF, in Spanish)

← Back to the Instituto Europeo de Fertilidad profile

Source: “Registro Nacional de Actividad 2023-Registro SEF” (Spanish National ART Activity Registry) — registrosef.com, retrieved 31 July 2026.