Skip to content
ClinicasReproduccionAsistida.es

MINIFIV, year by year

Everything the Spanish National Activity Registry publishes about MINIFIV between 2014 and 2023: 10 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.

Volume first

Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.

Transfers recorded per year — IVF/ICSI with own oocytes
’14’15’16534’17’18’19’20’21’22’23
See this chart’s data
Transfers recorded per year — IVF/ICSI with own oocytes
YearValue
2014176
2015399
2016487
2017534
2018457
2019352
2020269
2021269
2022252
2023208
Transfers recorded per year — Egg donation
’14’15132’16’17’18’19’20’21’22’23
See this chart’s data
Transfers recorded per year — Egg donation
YearValue
20149
201517
2016132
201757
20198
202029
202121
202224
202324

Results, year by year

Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.

IVF/ICSI with own oocytes · Under 35
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
IVF/ICSI with own oocytes · Under 35
YearFresh embryosFrozen embryos
201434.9 – 65.1%31.2 – 83.1%
201511.2 – 37.5%16.7 – 42.9%
20166.5 – 32.4%13.7 – 41.3%
201723.6 – 57.6%21.2 – 46.7%
201831.8 – 72.6%35.1 – 72%
201916.3 – 56.5%7.7 – 42.3%
20207.8 – 51.1%40 – 93.3%
202121.7 – 78.3%24.9 – 69.8%
202221.7 – 78.3%22.5 – 57.5%
202310.7 – 52.5%23 – 54.8%
IVF/ICSI with own oocytes · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
IVF/ICSI with own oocytes · Between 35 and 39
YearFresh embryosFrozen embryos
201431.6 – 61.4%0.5 – 49.5%
201514.5 – 31.3%23.5 – 46%
201617.2 – 33.8%12.8 – 30.6%
201721.2 – 36.8%21 – 38.2%
201821.7 – 39.7%22.4 – 39.5%
201919.6 – 40.7%21.9 – 39.2%
202016.8 – 38.6%15.7 – 34.9%
20217.9 – 30.4%22.2 – 44.5%
202211.2 – 40.2%19 – 40.2%
202314.1 – 55.9%16.7 – 40.4%
IVF/ICSI with own oocytes · Over 40
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
IVF/ICSI with own oocytes · Over 40
YearFresh embryosFrozen embryos
20145.5 – 24.7%0 – 37.8%
20158.7 – 23%6.6 – 28.9%
20167.2 – 19.3%20.8 – 38.6%
20175.1 – 16.9%17.4 – 34.6%
20187.8 – 23.5%6.6 – 19.1%
20198.2 – 27.3%8.1 – 26.8%
20207.8 – 27.9%7.6 – 32.4%
20214.9 – 22.7%10.5 – 30.2%
20223.9 – 26.1%10.5 – 30.2%
20236.2 – 36.6%12.4 – 36.5%
Egg donation · Under 35
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
Egg donation · Under 35
YearFresh embryosFrozen embryos
2014100 – 100%—
201632.6 – 100%13.3 – 100%
2017—0 – 86.7%
2021—100 – 100%
2022—100 – 100%
2023—0 – 55.1%
Egg donation · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
Egg donation · Between 35 and 39
YearFresh embryosFrozen embryos
20140 – 100%—
201634.7 – 73%12 – 76.9%
2017—0 – 41%
2019—0 – 100%
2020—13.3 – 100%
2021—2.5 – 64.1%
2022—0.5 – 49.5%
2023100 – 100%0 – 46.5%
Egg donation · Over 40
  • Fresh embryos
  • Frozen embryos
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
Egg donation · Over 40
YearFresh embryosFrozen embryos
201428.9 – 100%—
2015—7.9 – 64.8%
201620.6 – 43.9%28 – 64.9%
2017—16.5 – 44%
2019—0 – 71.1%
2020—28.4 – 67.6%
2021—0 – 55%
2022—0 – 49.4%
2023—0 – 24%
AIH — artificial insemination (partner’s sperm) · Under 40
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 40
YearUnder 40
20140 – 26.8%
AIH — artificial insemination (partner’s sperm) · Under 35
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 35
YearUnder 35
20150 – 20.6%
20169.6 – 70.4%
2018100 – 100%
20190 – 82.9%
20200 – 46.5%
20210 – 62%
20220 – 31.6%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
YearBetween 35 and 39
20150 – 37.8%
20160 – 71.1%
20180 – 28.6%
20190 – 22.2%
20200 – 40.2%
20210 – 35.4%
20220 – 35.4%
202332.6 – 100%
AID — artificial insemination (donor sperm) · Under 40
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AID — artificial insemination (donor sperm) · Under 40
YearUnder 40
201411 – 47.4%
AID — artificial insemination (donor sperm) · Under 35
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AID — artificial insemination (donor sperm) · Under 35
YearUnder 35
20150 – 22.2%
20160 – 32.6%
201710 – 90%
20180 – 55.1%
20191.6 – 58.4%
20200 – 22.2%
20210 – 26.1%
20220 – 35.4%
20230 – 42.9%
AID — artificial insemination (donor sperm) · Between 35 and 39
0255075100'14'15'16'17'18'19'20'21'22'23
See this chart’s data
AID — artificial insemination (donor sperm) · Between 35 and 39
YearBetween 35 and 39
20150 – 23.1%
20170 – 22.1%
20180 – 25.7%
20200 – 28.6%
20214.3 – 49%
20220 – 15.3%
20230 – 25.6%

Year-by-year table

The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.

YearName in the registryCycles startedTransfersPregnancy per transfer (under 35)Pregnancy per cycle (insemination)Attribution
2014MINIFIV100-50018534.9 – 65.1%0 – 26.8%Registro Nacional de Actividad 2014-Registro SEF
2015MINIFIV> 500 · 100-50041611.2 – 37.5%0 – 20.6%Registro Nacional de Actividad 2015-Registro SEF
2016MINIFIV> 500 · 100-5006196.5 – 32.4%9.6 – 70.4%Registro Nacional de Actividad 2016-Registro SEF
2017MINIFIV> 500 · 100-50059123.6 – 57.6%10 – 90%Registro Nacional de Actividad 2017-Registro SEF
2018MINIFIV> 500 · 100-50045731.8 – 72.6%100 – 100%Registro Nacional de Actividad 2018-Registro SEF
2019MINIFIV> 500 · 100-50036016.3 – 56.5%0 – 82.9%Registro Nacional de Actividad 2019-Registro SEF
2020MINIFIV> 500 · 100-5002987.8 – 51.1%0 – 46.5%Registro Nacional de Actividad 2020-Registro SEF
2021MINIFIV> 500 · 100-50029021.7 – 78.3%0 – 62%Registro Nacional de Actividad 2021-Registro SEF
2022MINIFIV100-50027621.7 – 78.3%0 – 31.6%Registro Nacional de Actividad 2022-Registro SEF
2023MINIFIV100-50023210.7 – 52.5%32.6 – 100%Registro Nacional de Actividad 2023-Registro SEF

Gaps in the series, and how to read them

The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.

The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.

And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.

Official guide: how to interpret a centre’s data (PDF, in Spanish)

← Back to the MINIFIV profile

Source: “Registro Nacional de Actividad 2023-Registro SEF” (Spanish National ART Activity Registry) — registrosef.com, retrieved 31 July 2026.