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Centro Gutenberg, year by year

Everything the Spanish National Activity Registry publishes about Centro Gutenberg between 2009 and 2023: 15 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.

Volume first

Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.

Transfers recorded per year — IVF/ICSI with own oocytes
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Transfers recorded per year — IVF/ICSI with own oocytes
YearValue
2009430
2010437
2011386
2012375
2013397
2014408
2015418
2016463
2017416
2018507
2019499
2020397
2021505
2022446
2023470
Transfers recorded per year — Egg donation
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Transfers recorded per year — Egg donation
YearValue
2009124
2010125
2011135
2012160
2013147
2014137
2015141
2016164
2017125
2018122
2019114
202076
2021127
2022104
2023100

Results, year by year

Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.

IVF/ICSI with own oocytes · Under 35
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Under 35
YearFresh embryosFrozen embryos
200943.2 – 57.3%47.7 – 61.6%
201043.5 – 57.5%54.6 – 68.3%
201147.7 – 62.3%63.4 – 76.8%
201248.8 – 65.7%63.5 – 78.6%
201349.4 – 67.7%65.3 – 80.9%
201446.8 – 66.6%57.6 – 86.9%
201551.4 – 71.2%41.1 – 69.5%
201645.2 – 64.2%47.5 – 69.8%
201748.2 – 72.4%48.4 – 72.9%
201846.1 – 68.5%51.3 – 74.8%
201940.8 – 63.1%54.6 – 76.1%
202037.5 – 67%50.4 – 73.8%
202131.8 – 56.7%39.8 – 59.3%
202231.3 – 60%45.5 – 68.7%
202343.3 – 72.2%52.9 – 71.8%
IVF/ICSI with own oocytes · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Between 35 and 39
YearFresh embryosFrozen embryos
200940.3 – 55.5%43 – 58.1%
201031.1 – 45.3%39.3 – 54%
201134.7 – 49.5%37.4 – 52.3%
201243.3 – 60.6%43.2 – 59%
201333.4 – 49.4%33.7 – 48.6%
201440.6 – 57.8%42.4 – 76.4%
201546.1 – 63.6%24.9 – 54.1%
201635.8 – 52.5%23.4 – 52.8%
201740.4 – 58.7%40.8 – 65.6%
201837.9 – 54.7%31.6 – 54.5%
201938.8 – 57.5%32.4 – 52.1%
202040.2 – 62.4%42 – 64.6%
202125.4 – 42.4%39.2 – 58.8%
202234.7 – 54.2%39.1 – 58.1%
202332.9 – 53.1%30.5 – 48.7%
IVF/ICSI with own oocytes · Over 40
  • Fresh embryos
  • Frozen embryos
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IVF/ICSI with own oocytes · Over 40
YearFresh embryosFrozen embryos
20098.7 – 23%8.7 – 23%
201015.3 – 31.4%17.8 – 34.5%
201113 – 29%16.8 – 33.9%
20125.7 – 25.7%6.6 – 25.1%
201311.5 – 30.2%11.8 – 27.6%
201427.1 – 46.8%9.2 – 47.9%
201517.5 – 35.2%31.9 – 80.6%
201623.4 – 43.2%12.6 – 58%
201717.4 – 34.6%0 – 40.2%
201813.8 – 28.6%13.3 – 40.4%
201916.7 – 33.8%19.6 – 48.7%
202022.7 – 44%28.1 – 53.2%
202116.7 – 36.7%22.7 – 49.3%
202214.8 – 34.5%29.5 – 56.7%
202315.7 – 34.9%13.3 – 40.4%
Egg donation · Under 35
  • Fresh embryos
  • Frozen embryos
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Egg donation · Under 35
YearFresh embryosFrozen embryos
200928.1 – 78.6%42.8 – 90.5%
201050.5 – 99.5%65.4 – 100%
201144.1 – 94.3%85.7 – 100%
201238.8 – 86.2%76.7 – 100%
201335.9 – 97.5%52 – 100%
201464.6 – 100%10 – 90%
201544.1 – 94.3%32.6 – 100%
201632.6 – 100%17.1 – 100%
2017100 – 100%100 – 100%
201813.3 – 100%—
20190 – 86.7%1 – 99%
2020—1 – 99%
2021100 – 100%—
2022100 – 100%28.9 – 100%
20231 – 99%2.5 – 64.1%
Egg donation · Between 35 and 39
  • Fresh embryos
  • Frozen embryos
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Egg donation · Between 35 and 39
YearFresh embryosFrozen embryos
200945.2 – 77%59.2 – 88%
201040.7 – 74.4%43.6 – 77%
201142.3 – 75.4%74 – 97.5%
201236.3 – 76.8%49.6 – 86.9%
201340.8 – 79.2%73.8 – 100%
201442 – 87.4%25.1 – 84%
201544.9 – 88.4%45 – 100%
201648.9 – 84.4%0 – 35.4%
201731 – 73.7%35.9 – 97.5%
201851 – 95.7%42.8 – 90.5%
201941.6 – 98.4%12 – 76.9%
20200 – 82.9%6.2 – 79.5%
202129.6 – 90.4%16.3 – 56.5%
202245 – 100%29.6 – 90.4%
202364.6 – 100%4 – 71%
Egg donation · Over 40
  • Fresh embryos
  • Frozen embryos
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Egg donation · Over 40
YearFresh embryosFrozen embryos
200942.8 – 64.9%49.1 – 70.9%
201045.4 – 66.8%54.5 – 75.2%
201150.8 – 70.5%61.9 – 80.2%
201252.1 – 72.7%76.8 – 91.9%
201359.9 – 80.7%100 – 100%
201454.9 – 77.4%36.8 – 74.3%
201549 – 72.9%30.3 – 63.8%
201647.2 – 68.5%49.5 – 80.2%
201748.4 – 72.9%51.5 – 87%
201852.9 – 78%36.2 – 69.7%
201939.7 – 69.8%21 – 48.5%
202022.2 – 59.3%37.6 – 71.5%
202148.2 – 79.6%41.4 – 67.7%
202242.2 – 74.4%28.7 – 59.1%
202351.9 – 83.4%43.6 – 75.3%
AIH — artificial insemination (partner’s sperm) · Under 40
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AIH — artificial insemination (partner’s sperm) · Under 40
YearUnder 40
200910.9 – 19.3%
20106.9 – 13.3%
201113.5 – 21.9%
201212.7 – 21.1%
20139 – 17.1%
20146.2 – 14.3%
AIH — artificial insemination (partner’s sperm) · Under 35
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AIH — artificial insemination (partner’s sperm) · Under 35
YearUnder 35
201511.1 – 26.2%
201611.4 – 28.2%
20176.1 – 22.5%
20187.9 – 26.4%
20197.1 – 25.7%
20204.2 – 27.4%
20217.5 – 29.2%
20223.4 – 23.3%
202318.6 – 50%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
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AIH — artificial insemination (partner’s sperm) · Between 35 and 39
YearBetween 35 and 39
201510.5 – 27.1%
20166.1 – 24.4%
20178.2 – 28.9%
20184.7 – 25.1%
20194.9 – 22.7%
20200 – 10.2%
20211.2 – 26.3%
202213.1 – 45%
202313.1 – 45%
AID — artificial insemination (donor sperm) · Under 40
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AID — artificial insemination (donor sperm) · Under 40
YearUnder 40
200913 – 24.5%
201013.3 – 25.1%
201115.6 – 29.9%
201212.2 – 25.4%
201313.3 – 25.5%
201410.5 – 22.6%
AID — artificial insemination (donor sperm) · Under 35
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AID — artificial insemination (donor sperm) · Under 35
YearUnder 35
20159.3 – 27.3%
201610.1 – 34.4%
20179.6 – 31.1%
201813.1 – 42.4%
20190.9 – 22.6%
202010.6 – 60.8%
202116.9 – 68.8%
20222.5 – 37.5%
20233 – 41.4%
AID — artificial insemination (donor sperm) · Between 35 and 39
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AID — artificial insemination (donor sperm) · Between 35 and 39
YearBetween 35 and 39
20159.7 – 27.1%
20166.9 – 27.1%
20174.1 – 22.3%
20185.8 – 26.2%
20192 – 20.7%
20206.9 – 39.3%
20216 – 44%
202228.1 – 71.9%
20232.5 – 37.5%

Year-by-year table

The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.

YearName in the registryCycles startedTransfersPregnancy per transfer (under 35)Pregnancy per cycle (insemination)Attribution
2009Centro Gutenberg> 500 · 100-50055443.2 – 57.3%10.9 – 19.3%Registro Nacional de Actividad 2009-Registro SEF
2010Centro Gutenberg> 500 · 100-50056243.5 – 57.5%6.9 – 13.3%Registro Nacional de Actividad 2010-Registro SEF
2011Centro Gutenberg> 500 · 100-50052147.7 – 62.3%13.5 – 21.9%Registro Nacional de Actividad 2011-Registro SEF
2012Centro Gutenberg> 500 · 100-50053548.8 – 65.7%12.7 – 21.1%Registro Nacional de Actividad 2012-Registro SEF
2013Centro Gutenberg> 500 · 100-50054449.4 – 67.7%9 – 17.1%Registro Nacional de Actividad 2013-Registro SEF
2014Centro Gutenberg> 500 · 100-50054546.8 – 66.6%6.2 – 14.3%Registro Nacional de Actividad 2014-Registro SEF
2015Centro Gutenberg> 500 · 100-50055951.4 – 71.2%11.1 – 26.2%Registro Nacional de Actividad 2015-Registro SEF
2016Centro Gutenberg100-50062745.2 – 64.2%11.4 – 28.2%Registro Nacional de Actividad 2016-Registro SEF
2017Centro Gutenberg> 500 · 100-50054148.2 – 72.4%6.1 – 22.5%Registro Nacional de Actividad 2017-Registro SEF
2018Centro Gutenberg> 500 · 100-50062946.1 – 68.5%7.9 – 26.4%Registro Nacional de Actividad 2018-Registro SEF
2019Centro Gutenberg> 500 · 100-50061340.8 – 63.1%7.1 – 25.7%Registro Nacional de Actividad 2019-Registro SEF
2020Centro Gutenberg> 500 · 100-50047337.5 – 67%4.2 – 27.4%Registro Nacional de Actividad 2020-Registro SEF
2021Centro Gutenberg> 500 · 100-50063231.8 – 56.7%7.5 – 29.2%Registro Nacional de Actividad 2021-Registro SEF
2022Centro Gutenberg> 500 · 100-50055031.3 – 60%3.4 – 23.3%Registro Nacional de Actividad 2022-Registro SEF
2023Centro Gutenberg> 500 · 100-50057043.3 – 72.2%18.6 – 50%Registro Nacional de Actividad 2023-Registro SEF

Gaps in the series, and how to read them

The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.

The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.

And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.

Official guide: how to interpret a centre’s data (PDF, in Spanish)

← Back to the Centro Gutenberg profile

Source: “Registro Nacional de Actividad 2023-Registro SEF” (Spanish National ART Activity Registry) — registrosef.com, retrieved 31 July 2026.