Everything the Spanish National Activity Registry publishes about Instituto de Reproducción CEFER between 2014 and 2023: 10 years with data. Each year carries its own attribution, because each year is a separate publication of the registry.
Volume first
Activity comes before results on purpose: a high percentage over few cycles does not mean what the same percentage over many cycles means. The registry publishes cycles as bands and that is how we show them, never reduced to a single figure; transfers are an exact count.
Transfers recorded per year — IVF/ICSI with own oocytesSee this chart’s data
Transfers recorded per year — IVF/ICSI with own oocytes
Year
Value
2014
166
2015
384
2016
463
2017
427
2018
483
2019
479
2020
336
2021
178
2022
162
2023
171
Transfers recorded per year — Egg donationSee this chart’s data
Transfers recorded per year — Egg donation
Year
Value
2014
157
2015
163
2016
122
2017
253
2018
130
2019
314
2020
62
2021
81
2022
108
2023
97
Results, year by year
Each band is the interval the registry published that year: the floor and the ceiling of the estimate, not a point. There is no line joining the years, and that is deliberate — joining the centres of successive intervals would assert a trend the data does not support.
IVF/ICSI with own oocytes · Under 35
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Under 35
Year
Fresh embryos
Frozen embryos
2014
30.9 – 63.5%
11 – 47.4%
2015
32.7 – 54%
30.5 – 56.7%
2016
26.1 – 47.3%
31.3 – 54.5%
2017
22.8 – 51.7%
17.7 – 34.2%
2018
9.4 – 28.7%
11.4 – 28.2%
2019
6.6 – 28.9%
8.8 – 21.9%
2020
7.8 – 51.1%
22.4 – 42%
2021
4 – 71%
20.4 – 51.8%
2022
0 – 86.7%
12.7 – 41.3%
2023
0 – 71.1%
10.8 – 42.5%
IVF/ICSI with own oocytes · Between 35 and 39
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Between 35 and 39
Year
Fresh embryos
Frozen embryos
2014
14.1 – 40.4%
2.5 – 37.5%
2015
23 – 40.1%
24.8 – 50.2%
2016
20.9 – 36.2%
20 – 38.7%
2017
21.5 – 46.3%
18.7 – 34.8%
2018
11.9 – 27.3%
10.4 – 26.1%
2019
20.2 – 42.5%
5.8 – 17.9%
2020
19.1 – 49.3%
23.8 – 42.2%
2021
3.8 – 46.2%
38.8 – 67.9%
2022
15.2 – 58.5%
9.9 – 36.3%
2023
7.8 – 51.1%
25.2 – 51.7%
IVF/ICSI with own oocytes · Over 40
Fresh embryos
Frozen embryos
See this chart’s data
IVF/ICSI with own oocytes · Over 40
Year
Fresh embryos
Frozen embryos
2014
1.1 – 24.7%
1 – 53.6%
2015
0 – 12.6%
4.1 – 34.4%
2016
1.8 – 19.5%
7.2 – 30.9%
2017
1.8 – 19.1%
12.2 – 34.3%
2018
0.9 – 11%
1.5 – 17%
2019
8.4 – 27.7%
7.3 – 23.1%
2020
7.2 – 30.9%
19.9 – 45.4%
2021
4.1 – 34.4%
0.5 – 16.5%
2022
1.4 – 28.2%
0.8 – 20.8%
2023
0 – 14.6%
13.4 – 38.8%
Egg donation · Under 35
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Under 35
Year
Fresh embryos
Frozen embryos
2014
—
0 – 67.4%
2015
32.6 – 100%
6.2 – 79.5%
2016
1 – 99%
38 – 100%
2017
100 – 100%
5.6 – 42%
2018
0 – 86.7%
0 – 67.4%
2019
0 – 100%
4.3 – 49%
2022
—
4 – 71%
2023
—
0 – 86.7%
Egg donation · Between 35 and 39
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Between 35 and 39
Year
Fresh embryos
Frozen embryos
2014
35.9 – 97.5%
0 – 35%
2015
13.8 – 69.6%
11.6 – 55.1%
2016
0 – 82.9%
1 – 53.6%
2017
0 – 49.4%
9.9 – 50.1%
2018
13.3 – 100%
0 – 62%
2019
0 – 67.4%
5.2 – 32.3%
2020
100 – 100%
32.6 – 100%
2021
0 – 67.4%
23.1 – 88%
2022
—
50.6 – 100%
2023
—
50.6 – 100%
Egg donation · Over 40
Fresh embryos
Frozen embryos
See this chart’s data
Egg donation · Over 40
Year
Fresh embryos
Frozen embryos
2014
26.6 – 50.3%
16.6 – 39.1%
2015
39.2 – 64.1%
19.9 – 43.4%
2016
30.1 – 56.7%
21.2 – 50.2%
2017
32.5 – 61.1%
22 – 36.4%
2018
30.9 – 63.5%
19.6 – 40.1%
2019
23.5 – 59.3%
10.5 – 19.7%
2020
15.4 – 84.6%
29.7 – 57.8%
2021
2.5 – 64.1%
19.1 – 42.9%
2022
—
27.4 – 47.6%
2023
28.9 – 100%
20.5 – 41%
AIH — artificial insemination (partner’s sperm) · Under 40See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 40
Year
Under 40
2014
1.7 – 18.7%
AIH — artificial insemination (partner’s sperm) · Under 35See this chart’s data
AIH — artificial insemination (partner’s sperm) · Under 35
Year
Under 35
2015
0 – 18.4%
2016
5.3 – 24.3%
2017
4 – 19.1%
2018
1.7 – 18.7%
2019
10.1 – 32.3%
2021
0 – 24%
2023
0 – 44.8%
AIH — artificial insemination (partner’s sperm) · Between 35 and 39See this chart’s data
AIH — artificial insemination (partner’s sperm) · Between 35 and 39
Year
Between 35 and 39
2015
3 – 28.2%
2016
1.6 – 30.4%
2017
5.4 – 33.3%
2018
0 – 19.4%
2019
3.9 – 33.2%
2021
0 – 31.6%
AID — artificial insemination (donor sperm) · Under 40See this chart’s data
AID — artificial insemination (donor sperm) · Under 40
Year
Under 40
2014
20.6 – 37.9%
AID — artificial insemination (donor sperm) · Under 35See this chart’s data
AID — artificial insemination (donor sperm) · Under 35
Year
Under 35
2015
13.4 – 33.6%
2016
8.7 – 23.6%
2017
12.2 – 27.8%
2018
16 – 32.6%
2019
4.4 – 15.5%
2020
18.3 – 42.4%
2021
4.6 – 21.6%
2022
20 – 46.7%
2023
9 – 33.8%
AID — artificial insemination (donor sperm) · Between 35 and 39See this chart’s data
AID — artificial insemination (donor sperm) · Between 35 and 39
Year
Between 35 and 39
2015
11.4 – 33.9%
2016
4 – 19.1%
2017
17 – 38.1%
2018
2.7 – 13.6%
2019
8.3 – 20.7%
2020
8.7 – 24.6%
2021
7.4 – 17.7%
2022
9.5 – 25.8%
2023
4.5 – 17.2%
Year-by-year table
The table is the exact and complete reading: everything in the charts, and more. Each row cites the wording the registry requires for that year.
Year
Name in the registry
Cycles started
Transfers
Pregnancy per transfer (under 35)
Pregnancy per cycle (insemination)
Attribution
2014
Instituto de Reproducción CEFER
100-500
323
30.9 – 63.5%
1.7 – 18.7%
Registro Nacional de Actividad 2014-Registro SEF
2015
Instituto de Reproducción CEFER
100-500
547
32.7 – 54%
0 – 18.4%
Registro Nacional de Actividad 2015-Registro SEF
2016
Instituto de Reproducción CEFER
100-500
585
26.1 – 47.3%
5.3 – 24.3%
Registro Nacional de Actividad 2016-Registro SEF
2017
Instituto de Reproducción CEFER
100-500
680
22.8 – 51.7%
4 – 19.1%
Registro Nacional de Actividad 2017-Registro SEF
2018
Instituto de Reproducción CEFER
100-500
613
9.4 – 28.7%
1.7 – 18.7%
Registro Nacional de Actividad 2018-Registro SEF
2019
Instituto de Reproducción CEFER
100-500
793
6.6 – 28.9%
10.1 – 32.3%
Registro Nacional de Actividad 2019-Registro SEF
2020
Instituto de Reproducción CEFER
100-500
398
7.8 – 51.1%
18.3 – 42.4%
Registro Nacional de Actividad 2020-Registro SEF
2021
Instituto de Reproducción CEFER
100-500
259
4 – 71%
0 – 24%
Registro Nacional de Actividad 2021-Registro SEF
2022
Instituto de Reproducción CEFER
100-500
270
0 – 86.7%
20 – 46.7%
Registro Nacional de Actividad 2022-Registro SEF
2023
Instituto de Reproducción CEFER
100-500
268
0 – 71.1%
0 – 44.8%
Registro Nacional de Actividad 2023-Registro SEF
Gaps in the series, and how to read them
The registry’s province-by-province census returns empty for 2009 and 2010, even though the individual profiles for those years do exist and have been recovered one by one. A centre missing from a given year means the registry publishes no profile for it that year — not that it closed.
The registry’s template changed schema in 2014 and again in 2015: up to 2013, cycles, implantation and transfers are published without separating fresh from frozen embryos, and insemination is published for a single age band (“under 40”). That is why some years carry fewer series than others: it is what the source published, not a missing figure.
And most important: a change from one year to the next is not, on its own, an improvement or a decline. The patient mix changes, selection criteria change and, at small volumes, chance changes too. Wide intervals are precisely the signal that the exact number cannot be trusted.
